补产肠补尘抗体
英文名:PE-Cy™7 Mouse Anti-Human CD16
克隆号:Clone 3G8 (RUO)
介绍:
Brand
BD Pharmingen™
Vol. Per Test
5 µl
Isotype
Mouse BALB/c x DBA/2, also known as CD2F1 or CDF1 IgG1, κ
Reactivity
Human (QC Testing) Rhesus, Cynomolgus, Baboon (Reported)
Application
Flow cytometry (Routinely Tested)
Immunogen
Human polymorphonuclear leukocytes
Workshop No.
IV N409
Entrez Gene ID
2214 2215
Storage Buffer
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Regulatory Status
RUO
补产肠补尘抗体规格
100 Tests 25 Tests
货号
557744
补产肠补尘抗体 介绍
The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al., 1997) to increase intracellular calcium levels in human neutrophils by interacting with bothFcγRIIa and FcγRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation.
Format
PE-Cy™7
Excitation Source
Blue 488 nm,Green 532 nm,Yellow/Green 561 nm
Excitation Max
496 nm
Emission Max
785 nm
PE-Cy™7 is a tandem fluorochrome that combines PE and a cyanine dye. PE-Cy7 conjugated reagents are as bright as PE conjugates. PE-Cy7 is particularly sensitive to photo-induced degradation, resulting in loss of fluorescence and changes in fluorescence spillover. Extreme caution must be taken to avoid light exposure and prolonged exposure to paraformaldehyde fixative. Fixed cells should be analyzed within 4 hours of fixation in paraformaldehyde or transferred to a paraformaldehyde-free buffer for overnight storage.
Cat No. | Description | Size | |
---|---|---|---|
557872 | PE-Cy™7 Mouse IgG1 κ Isotype Control RUO | 100 Tests |
系列
础产肠补尘目前提供超过10000种优质的神经生物学抗体相关产物,并且不断的进行产物的更新和添加;包括以下系列:
ü 神经标志物抗体:GFAP、GAP43、Gli1
ü 神经退行性病变相关抗体:如beta Amyloid 1-42,APP
ü 神经递质抗体:如GAT1/2/3
ü 神经生长和发育相关抗体:如Nestin
ü 知觉传递通路抗体
ü 其它神经生物学相关抗体